The Cost of Stem Cell Therapy in 2023

Louis A. Cona, MD
Updated on
May 23, 2023

This article explains the costs associated with different stem cell treatments, what will impact the price, and why stem cell therapy may be a good alternative to traditional medications.

The Cost of Stem Cell Therapy in 2023

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How much does stem cell treatment cost?

Stem cell therapy costs can range anywhere from $5000-$50,000 USD. Treatment cost will vary dramatically depending on a variety of different factors.

Stem cell therapy cost can be influenced by:

  1. The type of stem cells administered
  2. How many cells are administered
  3. The quality of the cells (are the ethically sourced, viable & regulated?)
  4. Where the laboratory is located (for cell expansion)
  5. The source of stem cells (umbilical cord tissue, adipose tissue, bone marrow, etc.)

It is also important to note that the cost of stem cell therapy will vary depending on the type of treatment needed. The cost of a site injection for an orthopedic condition will be significantly different than an intravenous treatment for an autoimmune condition.


Average Cost of Stem Cell Therapy

The average stem cell therapy cost can range anywhere between $5000 - $50,000. Patients must do their research and ask as many questions as they can before financially committing to treatment. Make sure to know how many cells you are getting, where those cells come from, if they are viable, is the clinic/lab is regulated, and ask for as detailed info to be provided as possible. When considering a potentially life-changing treatment, prospective patients should be weighing these other important factors, in addition to cost, when determining the best location for experimental procedures.

The cost of stem cell therapy at DVC Stem

DVC Stem is an innovative stem cell therapy clinic in the Cayman Islands. The clinic’s Medical Director, Dr. Cona, is a pioneer in regenerative cell therapy, providing the first stem cell treatments in the Cayman Islands more than a decade ago. He continues to research alternative therapies for various medical conditions, and with IRB certified clinical trials, has treated local and international patients for Multiple Sclerosis (MS), Chronic Low Grade Inflammation (which is part of the overall Aging Process), and many other degenerative conditions. DVC Stem's IRB-approved mesenchymal stem cell protocol is currently priced at $25,000 USD.

The cost of stem cell therapy
The cost of stem cell therapy infographic

Stem cell umbilical cord cost

The cost of private cord blood banking ranges from $300 to $2,300 for collection, processing and initial storage, with additional annual storage fees after that. Stem cell therapy can costs can range anywhere from $5000-$50,000 USD, with the average cost of treatment at DVC Stem costs $25,000 USD.

How does the stem cell clinic influence the cost of treatment?

There are several factors that can influence the cost of treatment at a stem cell clinic, including:

  1. The type of stem cells being used: Adult stem cells are generally less expensive to obtain and process than embryonic stem cells.
  2. The specific condition being treated: Some conditions may require more complex or expensive treatments than others.
  3. The location of the clinic: Stem cell clinics located in major cities or in areas with high demand for stem cell therapies may charge higher prices.
  4. The reputation and experience of the medical team: Clinics with a track record of successful treatments and highly qualified medical professionals may charge higher fees.
  5. The stem cell product: higher quality stem cell product will cost more to produce. It is important to note that cell quality directly correlates with treatment safety and efficacy.
  6. Regulation: Adhering to regulations imposed by the governing country will impact the cost of treatment - it will also promote treatment safety and effectiveness.

It is important for patients to carefully research the costs of treatment at different stem cell clinics and to consider all of these factors when making a decision about where to receive treatment.

How much does stem cell therapy cost?

Stem cell therapies have become very popular in recent years, as people are seeking the latest alternative treatments for their many conditions. More and more types of therapies are being introduced every day, and people around the world are turning to them and rejecting traditional regimens of drugs and hospital visits. However, despite the large surge in demand for stem cell therapies, they still remain very expensive to pursue. Even simple joint injections can cost nearly $5000 and more advanced treatments can rise in cost up to $100,000 depending on the condition.

Stem cell therapy cost for knees or a degenerative condition such as Crohn's Disease may differ from stem cell therapy cost for COPD (Chronic Obstructive Pulmonary Disease). The area and issue being treated should generally influence the cost of the associated treatment because different cell types, cell counts and treatment protocols will be needed. For example, an effective stem cell therapy cost for MS will be much different than the cost of a site injection for localized pain.


The Importance of Regulation in Ensuring Safety and Impact on Treatment Cost for Mesenchymal Stem Cell Therapies

Regulation is crucial to ensure the safety and efficacy of mesenchymal stem cell (MSC) treatments, as it helps to maintain high standards for their production, application, and monitoring. Without proper regulatory oversight, there is a risk of administering MSC treatments with suboptimal quality, leading to potential adverse effects or reduced therapeutic benefits for patients.

One key aspect of regulation involves establishing guidelines for the isolation, expansion, and characterization of MSCs to ensure that the cells used in therapies are consistent, viable, and free from contamination. Another vital component of regulation is the establishment of clinical trial protocols, which are designed to systematically evaluate the safety and effectiveness of MSC-based therapies in various medical conditions. Regulatory agencies, such as the FDA, require that new treatments undergo rigorous testing before they can be approved for widespread use.

Although regulation plays a crucial role in ensuring the safety of MSC treatments, it can also contribute to increased treatment costs. The extensive testing and validation required by regulatory agencies can be time-consuming and expensive, as they involve multiple phases of clinical trials, often with large numbers of participants. Additionally, the need to maintain Good Manufacturing Practices (GMP) compliant facilities for MSC production adds to the overall cost of treatment, as these facilities must meet strict standards for sterility, quality control, and documentation.

Moreover, the regulatory approval process can be lengthy, which may delay the availability of MSC treatments to patients in need. Despite these challenges, the regulatory framework is essential in maintaining the safety and efficacy of MSC therapies, ultimately protecting patients and ensuring that they receive the highest quality care. The increased costs associated with regulation can be considered an investment in the long-term success of MSC treatments, as they help to build trust among patients, healthcare providers, and stakeholders in the field of regenerative medicine.

COVID-19 stem cell treatment cost

DVC Stem offers a mesenchymal stem cell treatment protocol aimed at post-acute COVID-19 syndrome, the cost of this treatment is $25,000 USD. Patients can expect fewer long term complications, improved recovery time, a reduction in persistent COVID-19 related symptoms & an overall decrease in inflammation throughout the body.

The type of stem cells being administered

The type of stem cells being administered or regenerative therapy utilized plays a huge role in stem cell therapy costs. There are a few different types of cells, these can be mainly broken down into a few categories:

  1. Platelet Rich Plasma (PRP) injections
  2. Birth tissues (umbilical cord blood or amniotic fluid)
  3. Adipose (fat) tissue or bone marrow
  4. Allogenic culture-expanded stem cell procedure (umbilical cord tissue)

Platelet Rich Plasma Therapy

Platelet Rich Plasma (PRP) is typically administered via site injections directly into the affected area. This can be performed on the same day and requires no cell expansion, the same is true for umbilical cord blood.

Platelet Rich Plasma (PRP) and stem cells are distinct entities with different origins and functions, although both have been widely used in regenerative medicine. PRP is a concentrated solution derived from a patient's own blood, containing a high concentration of platelets, which are small, anucleate cell fragments that play a crucial role in blood clotting and wound healing. PRP is obtained by centrifuging a blood sample to separate the different blood components, allowing for the collection of a platelet-rich layer. The primary function of PRP is to release growth factors and cytokines that promote tissue repair, angiogenesis, and inflammation modulation. PRP has been used in various medical fields, including orthopedics, sports medicine, and dentistry, for its potential to accelerate healing and tissue regeneration.

Birth Tissues

Allogenic stem cell therapy consists of cells extracted from cord tissue, or “Wharton’s Jelly”. Umbilical cord tissue can have some of the most powerful, primal mesenchymal stem cells that can be found.  Studies have shown that stem cells, at the point of birth are at their peak of potency, unaffected by the aging process or disease. However the administration of culturally expanded cells in the United States is largely not authorized according to FDA sections 351 and 361. Stem cell therapy cost for culturally expanded cells ranges from USD 15,000 - USD 45,000. 

Adipose Tissue (Fat Derived Stem Cells)

Adipose (fat) stem cell procedures can also be performed the same day because they do not require cell expansion. Adipose (fat) and bone marrow stem cell treatments can be quite invasive because they require the cells to be extracted from the patient, which requires surgery.

These treatments can range from $4000 - $8,000 in the United States. Adipose (fat) and Bone Marrow stem cell treatments can be effective for certain orthopedic conditions, but studies have shown that they are not a viable treatment option for chronic widespread inflammation or autoimmune conditions due to a variety of factors including lower cell count and potency. This is what makes expanded cord tissue-derived stem cells so revolutionary.

The cost can influence stem cell therapy success rate

Increased costs and regulation can potentially increase the success rate of stem cell therapy in a few different ways.

First, increased costs may be necessary to fund research and development efforts aimed at improving the safety and effectiveness of stem cell therapies. This could involve investing in new technologies or conducting clinical trials to test the safety and efficacy of different treatments.

Second, increased regulation may help to ensure that stem cell therapies are developed and administered in a safe and ethical manner. For example, stricter regulations may be put in place to ensure that stem cells are obtained and processed in a way that minimizes the risk of contamination or other issues. This could help to increase the overall safety and reliability of stem cell treatments.

Overall, it is important to strike a balance between the need for increased funding and regulation to help improve the success rate of stem cell therapies, and the need to ensure that these treatments are accessible and affordable for patients.


The success rate at DVC Stem

We are currently still collecting long-term data and do not have any published results to share specifically related to our IRB-approved clinical study. However, preliminary data that has been collected over the past 4.5 years has been exciting.

Patient reported results have since shown that ~85% of our total patient population have noted a sustained improvement in their condition within 3 months of treatment. This data is measured via a follow-up vitality questionnaire that is compared to baseline results collected within 3 months prior to treatment in conjunction with unique inflammatory marker testing.

More specifically, the current average improvements for our  patients 3 months after treatment are as follows:

  • 75% increase in Stamina
  • 53.75% increase in Libido
  • 51.40% increase in Energy Levels
  • 43.97% increase in Balance
  • 28% increase in Coordination
  • 23.19% increase in Strength
  • 21% increase in Vision

Average improvements concerning cognitive function 12 months after treatment are as follows:

  • 19.84% improvement in Memory
  • 44% improvement in Ability to Concentrate
  • 31.94% improvement in Decision Making
  • 12.5% increase in Quality of Sleep

So why is stem cell therapy so expensive?

The short answer to that question is that the stem cell field is still highly specialized and has not been adopted by the mainstream and insurance companies. Additionally, the field is further restricted by older laws in the United States. That means that there are very few sources for stem cells, labs that are equipped to process stem cells, and reputable clinics that provide the treatments, most of which are located outside the US. Just as with an expensive food or item of clothing, the problem is with availability and production cost.

To fully understand the cost, you first have to look at the treatment preparation process. Stem cells are first acquired by companies that pay hospitals for donated cord tissue, or by doctors that perform fat tissue or bone marrow extractions. The cells are then sent to separate companies which run laboratories that specialize in stem cell expansion. These labs usually have very qualified and specialized staff members and are under the strict regulations of the FDA. The cells are then shipped in cryo-storage overnight around the world to the stem cell clinic. These clinics are staffed with doctors, nurses, and support staff that all play a part in the patient’s experience. This includes everything from marketing, to logistics and the actual medical care. In every stage of this process, there are heavy costs associated with time and labor, before the patient is ever given treatment.

Does stem cell therapy cost vary in different countries?

Yes it does, and that is highly dependent on the lab where the cells are acquired from, the total count of stem cells administered and the regulations the governing body places on the clinic. For example, stem cell therapy cost in Mexico will differ from stem cell therapy costs in Panama and Grand Cayman. For example, DVC Stem in Grand Cayman uses culturally expanded cord tissue-derived mesenchymal stem cells sourced from their cGMP, FDA compliant partner lab in the USA.

DVC Stem has the best stem cell treatment in the world and uses cells that are highly regulated by both the US and Cayman Islands governments. This can include but is not limited to, maintaining certifications, complying with regular government inspections, and having independently reviewed treatment protocols. These restrictions can raise the production and administration cost of treatment to the patient, but also ensures patient safety and the quality standards of the cell product. While it is possible to receive stem cell therapy in the United States, clinics cannot legally administer an expanded cell product. If you are looking for a local clinic a simple google search "stem cells near me" may suffice.


Stem cell treatment in Mexico

Mexico has become a popular destination for stem cell therapy, with many clinics offering treatment for a variety of conditions, including multiple sclerosis (MS). MS stem cell treatment in Mexico has gained attention as a potential alternative to traditional therapies, as it may help to reduce inflammation and improve function in patients with this chronic neurological condition.

Stem cell therapy in Mexico is also being explored as a treatment option for other conditions such as arthritis, Parkinson's disease, and spinal cord injuries. It is important to note that while stem cell therapy in Mexico may offer promising results, it is important to do your research and carefully evaluate the credentials and reputation of any stem cell clinic before undergoing treatment. It is also essential to consult with a qualified healthcare professional to determine if stem cell therapy is an appropriate treatment option for your specific condition.

Who is performing the procedure?

Stem cell therapy cost is linked to whoever performs the treatment. There are a few different types of medical providers that may have the ability to inject the cells.

  1. Nurse Practitioners & Physicians Assistants
  2. Physician Specialists (or a Medical Director)

Unfortunately, there is not always a positive correlation when it comes to comparing stem cell therapy cost with the level of training. When looking for a reputable clinic it is important to make sure that the treatment will be performed by a specialized physician.

For example, DVC Stem was founded by Dr. Louis A. Cona, he is the Medical Director of the facility and performs every single treatment with the help of a Registered Nurse (RN). Dr. Cona has over 15 years of experience in the field of Regenerative Medicine.

Are the cells ethically sourced, viable and regulated?

Stem cell therapy cost can also be associated with the quality of the cells being administered. How the cells are sourced can play a key role in stem cell therapy cost. For example regulations in Mexico and South America are much more lenient than those in the United States, allowing for cells to be acquired at a cheaper cost. However, there is a tradeoff, with less regulation it becomes tough to ensure the safety and viability of the cells.  For example stem cell therapy cost in Tijuana will be different from other places due to differences in regulation, cell manufacturing quality and cost of labour.

The American Association of Tissue Banks was created for this exact purpose. To regulate donated tissues and heavily screen them for infection and disease. DVC Stem uses umbilical cord tissue-derived cells from their partner lab who only sources their tissue from AATB certified suppliers of full term, human cord tissue.


How much do stem cell injections cost?

These treatments can range from $4000 - $8,000 in the United States. Adipose (fat) and Bone Marrow stem cell treatments can be effective for certain orthopedic conditions, but studies have shown that they are not a viable treatment option for chronic widespread inflammation or autoimmune conditions due to a variety of factors including lower cell count and potency.

This is what makes expanded cord tissue-derived stem cells so revolutionary. Infinity stem cell therapy may also provide data into the costs of stem cell therapy in the European market. A simple google search "the cost of stem cell injections near me" will usually showcase local clinics and the costs associated with treatment.

Allogenic stem cell therapy consists of cells extracted from cord tissue, or “Wharton’s Jelly”. Umbilical cord tissue can have some of the most powerful, primal mesenchymal stem cells that can be found.  Studies have shown that stem cells, at the point of birth are at their peak of potency, unaffected by the aging process or disease. However the administration of culturally expanded cells in the United States is largely not authorized according to FDA sections 351 and 361. Stem cell therapy cost for culturally expanded cells ranges from USD 15,000 - USD 45,000.

MS Patient at DVC Stem during treatment
Multiple Sclerosis Patient at DVC Stem during treatment.

How long do stem cell injections last?

This can be influenced by a variety of factors. To make things simple at DVC Stem, our stem cell clinic in Grand Cayman, we inject over 300 million mesenchymal stem cells intravenously (IV). Currently DVC Stem's treatment protocol does not call for a specific re-treatment period. If patients are happy with the results, no other treatment is necessary. We do have patients return to us on an annual basis voluntarily to maintain sustained benefit.

Does Medicare cover stem cell therapy?

Medicare also does not cover stem cell therapy in the United States or internationally. According to Medicare "Due to the experimental nature of most stem cell therapies, coverage through Medicare insurance for treatment with stem cell therapy is limited."

Legal Environment

Due to the nature of the laws in place, there are no forms of government assistance or incentives for any of these companies, unlike large drug companies. The cost of healthcare in the US is astronomical, but that is still with the large support structure in place for these healthcare companies. With no such support, the stem cell industry is left to provide treatment to patients, which incur most of the cost. It may be difficult to find a reputable stem cell therapy near me due to these limitations in the United States.

Without coverage by most major insurance providers, the only option for patients is either to pay for treatment outright, fundraise for their treatment, or use forms of financing to fund themselves. In many ways, stem cell therapies are not priced differently than many major drugs and treatments, but patients do not always see the cost when working through their insurance.

Stem cell therapy then becomes a personal choice. It is often sought after by patients that have had little success with conventional therapies, and wish to try an alternative. Stem cell medicine is still an emerging field and offers hope to many people to overcome their conditions.

Unfortunately, until stem cell medicine is more accepted into the mainstream and the laws are changed to encourage the field to develop, it will remain a highly specialized niche in healthcare. For this reason, treatment costs are not likely to change anytime soon. The best an inquiring patient can do is find a reputable clinic that provides treatments using the highest quality stem cells available to ensure they receive the best results possible.

The Cost Challenges of Exosome-based Therapies

Exosome-based therapies, while promising, currently face several challenges related to their cost. The manufacturing process for producing clinical-grade exosomes involves multiple steps, including cell culture, exosome isolation, purification, and characterization. Each of these steps requires specialized equipment, reagents, and expertise, contributing to the overall cost of producing exosomes.

Additionally, standardization and quality control measures need to be implemented to ensure the safety and efficacy of exosome products, further adding to the expenses. As a result, exosome therapies can be quite costly for patients and healthcare systems. However, as research and development in the field of exosome therapeutics continue to progress, it is expected that improvements in production methods, scalability, and regulatory frameworks will help to reduce the costs associated with exosome-based treatments, making them more accessible to a wider patient population.

Best stem cell clinic in the world

DVC Stem is one of the best stem cell clinics in the world that prioritizes both safety and efficacy in their treatments. With an IRB-approved treatment protocol, patients can trust that the treatments have undergone thorough review by an independent ethics committee to ensure their safety and rights.

DVC Stem's clinical study, "The Effects of Cord Tissue Derived MSCs on the Treatment of Chronic Low-Grade Inflammation," is registered with the government of the Cayman Islands, providing an additional level of oversight and transparency.

The clinic's stem cells are ethically sourced from AATB-certified, US-donated, full-term human umbilical cords and processed in an award-winning, FDA registered, cGMP compliant, ISO 9001 and ISO 13485 certified medical laboratory. The cells are also tested to ISCT standards for viability to ensure they meet minimum quality requirements multiple times before treatment.

The treatment protocol includes a two-day period of intravenous transplant of 300 million culturally expanded human umbilical cord tissue-derived adult mesenchymal stem cells (MSCs) and a variety of therapies designed to enhance stem cell activation and potency, such as physiotherapy, acupuncture, and lymphatic massage. The procedure is minimally invasive and has minimal downtime. All these factors make DVC Stem the best stem cell clinic in the world, offering a safe, effective and well-rounded treatment protocol with the oversight of government and independent agencies and use of high-quality stem cells.

Why choose DVC Stem for stem cell therapy?

DVC Stem is a stem cell therapy pioneer, offering stem cell therapies for years and has become a cornerstone of the medical tourism industry. Located in the tropical paradise of Grand Cayman in the Western Caribbean, we offer patients a nearby alternative to traveling long distances and to less ideal locations. Our protocols are IRB approved, and our cells come from regulated, U.S. based, FDA compliant laboratories. We seek to offer the highest quality products, the latest available treatments for a variety of conditions, all combined with a world-class setting and service.

Find out if you are eligible for stem cell therapy at DVC Stem

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